Research Papers from the CNE

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Kunovac-Kallak T, Hellgren C, Skalkidou A, Sandelin-Francke L, Ubhayasekera K, Bergquist J, Axelsson O, Comasco E, Campbell R, Sundstrom Poromaa I. (2017) Maternal and female fetal testosterone levels are associated with maternal age and gestational weight gain. Eur J. Endocrinol July 13 pii: EJE-17-0207. View abstract

Thomson-Laing G, Jasoni CL, Lokman MP. (2017) The effects of migratory stage and 11-ketotestosterone on the expression of rod opsin genes in the shortfinned eel (Anguilla australis). General and Comparative Endocrinology Jun 28. pii: S0016-6480(17)30460-4. View abstract

Moore AM, Campbell RE. (2017) Polycystic ovary syndrome: Understanding the role of the brain. Front Neuroendocrinol. May 25. pii: S0091-3022(17)30024-9. Review. View abstract

Rizwan MZ, Mehlitz S, Grattan DR, Tups A. (2017) Temporal and regional onset of leptin resistance in diet-induced obese mice.
J Neuroendocrinol. May 6. doi: 10.1111/jne.12481. [Epub ahead of print]. View abstract

Ancel C, Inglis MA, Anderson GM. (2017) Central RFRP-3 stimulates LH secretion in male mice and has cycle stage-dependent inhibitory effects in females. Endocrinology. May 4. doi: 10.1210/en.2016-1902. [Epub ahead of print]. View abstract

Kirk SE, Xie TY, Steyn FJ, Grattan DR, Bunn SJ. (2017) Restraint stress increases prolactin-mediated phosphorylation of signal transducer and activator of transcription 5 in the hypothalamus and adrenal cortex in the male mouse. J Neuroendocrinol. Apr 20. doi: 10.1111/jne.12477. [Epub ahead of print]. View abstract

Ladyman SR, MacLeod MA, Khant Aung Z, Knowles P, Phillipps HR, Brown RS, Grattan DR. (2017) Prolactin receptors in Rip-cre cells, but not in AgRP neurons, are involved in energy homeostasis. J Neuroendocrinol Apr 4. [Epub ahead of print]. View abstract

Gustafson P, Kokay I, Sapsford T, Bunn S, Grattan D. (2017) Prolactin regulation of the HPA axis is not mediated by a direct action upon CRH neurons: evidence from the rat and mouse. Brain Struct Funct. Mar 23. View abstract

Tups A, Benzler J, Sergi D, Ladyman SR, Williams LM. (2017) Central Regulation of Glucose Homeostasis. Compr Physiol. Mar 16;7(2):741-764. View abstract

Egan OK, Inglis MA, Anderson GM. (2017). Leptin signalling in AgRP neurons modulates puberty onset and adult fertility in mice. J Neurosci. Mar 8. pii: 3138-16. View abstract

Iremonger KJ, Porteous R, Herbison AE. (2017). Spike and neuropeptide-dependent mechanisms control GnRH neuron nerve terminal Ca(2+) over diverse time scales. J Neurosci. Feb 24. pii: 2925-16. View abstract

Barad Z, Grattan DR, Leitch B. (2017). NMDA Receptor Expression in the Thalamus of the Stargazer Model of Absence Epilepsy. Sci Rep. Feb 21;7:42926. View abstract

Augustine RA, Ladyman SR, Bouwer GT, Alyousif Y, Sapsford TJ, Scott V, Kokay IC, Grattan DR, Brown CH. (2017). Prolactin regulation of oxytocin neurone activity in pregnancy and lactation. J Physiol Feb 17 [Epub ahead of print]. View abstract

Evans MC, Anderson GM. (2017). Neuroendocrine integration of nutritional signals on reproduction. J Mol Endocrinol. 7 Feb;58(2):R107-R128. Review. View abstract

Booker C, Grattan DR. (2017) IL1R9 Is Evolutionarily Related to IL18BP and May Function as an IL-18 Recepto. J.immunol.Jan 1;198(1):270-278. View abstract

Seymour AJ, Scott V., Augustine RA, Bouwer GT, Campbell RE & Brown CH (2017). Development of an excitatory kisspeptin projection to the oxytocin system in late pregnancy. J. Physiol. Feb 1;595(3):825-838. View abstract



Brown RS, Kokay IC, Phillipps HR, Yip SH, Gustafson P, Wyatt A, Larsen CM, Knowles P, Ladyman SR, LeTissier P, Grattan D. (2016) Conditional Deletion of the Prolactin Receptor Reveals Functional Subpopulations of Dopamine Neurons in the Arcuate Nucleus of the Hypothalamus. J Neurosci. Aug 31;36(35):9173-85. View abstract

CNE Best Paper of the Year 2016

Czieselsky K, Prescott M, Porteous R,  Campos P, Clarkson J, Steyn FJ, Campbell RE, Herbison AE.  (2016) Pulse and Surge Profiles of Luteinizing Hormone Secretion in the Mouse. Endocrinology  Dec;157(12):4794-4802. View abstract

Jenkins DE, Sreenivasan D, Carman F, Babru S, Eiden LE, Bunn SJ. (2016) Interleukn-6 mediated signaling in adrenal medullary chromaffin cells. J Neurochem. Oct 22 jnc. 13870 [Epub ahead of print]. View abstract

Marshall CJ, Desroziers E, McLennan T, Campbell RE. (2016) Defining Subpopulations of Arcuate Nucleus GABA Neurons in Male, Female, and Prenatally Androgenized Female Mice. Neuroendocrinology 7 Oct [Epub ahead of print]. View abstract

Manfredi-Lozano M, Roa J, Ruiz-Pino F, Piet R, Garcia-Galiano D, Pineda R, Zamora A, Leon S, Sanchez-Garrido MA, Romero-Ruiz A, Dieguez C, Vazquez MJ, Herbison AE, Pinilla L, Tena-Sempere M. (2016) Defining a novel leptin-melanocortin-kisspeptin pathway involved in the metabolic control of puberty. Mol Metab Aug 11;5(10):844-57. View abstract

Brown C H. (2016) Magnocellular Neurons and Posterior Pituitary Function. Compr. Physiol 6:1701-1741. View abstract

Ladyman SR, Grattan DR. (2016) Central Effects of Leptin on Glucose Homeostasis are Modified during Pregnancy in the Rat. J Neuroendocrinol. Sep 13. jne.12431. View abstract

Seymour AJ, Scott V, Augustine RA, Bouwer GT, Campbell RE, Brown CH. (2016) Development of an excitatory kisspeptin projection to the oxytocin system in late pregnancy. J Physiol. Sep 2. JP273051. View abstract

Anderson GM. (2016) Tet Enzymes: Developmental Fleas of Gnrh Gene Methylation. Endocrinology Sep;157(9):3398-9. View abstract

Kim JS, Brown CH, Anderson GM. (2016) Anti-opioid effects of RFRP-3 on magnocellular neuron activity in morphine-naïve and morphine-treated female rats. Endocrinology Aug 17:en20161374. View abstract

Piet R, Dunckley H, Lee K, Herbison AE. (2016) Vasoactive intestinal peptide excites GnRH neurons in male and female mice. Endocrinology Aug 8:en20161399. View abstract

Grattan DR. (2016) The Eyes Have it! Protective Role of Prolactin in the Retina. EBioMedicine Jun;8:26-7. View abstract

McEwen HJ, Inglis M, Quennell JH, Grattan DR, Anderson GM. (2016) Deletion of Suppressor of Cytokine Signaling 3 from Forebrain Neurons Delays Infertility and Onset of Hypothalamic Leptin Resistance in Response to a High Caloric Diet. J Neurosci Jul 6;36(27):7142-53. View abstract

Kim JS. What's in a name? Roles of RFamide-related peptides beyond gonadotropin inhibition. J Neuroendocrinol. 2016 Jul. View abstract

Kim DW, Glendining KA, Grattan DR, Jasoni CL.(2016) Maternal obesity leads to increased proliferation and numbers of astrocytes in the developing fetal and neonatal mouse hypothalamus. Int J Dev Neurosci. Jun 17. pii:S0736-5748(16)30163-0. View abstract

Liu X, Herbison AE. (2016) Kisspeptin Regulation of Neuronal Activity throughout the Central Nervous System. Endocrinol Metab (Seoul) Jun;31(2):193-205. View abstract

Decourt C, Robert V, Anger K, Galibert M, Madinier JB, Liu X, Dardente H, Lomet D, Delmas AF, Caraty A, Herbison AE, Anderson GM, Aucagne V, Beltramo M. (2016) A synthetic kisspeptin analog that triggers ovulation and advances puberty. Sci Rep. Jun 1;6:26908. View abstract

Herbison AE. (2016) Control of puberty onset and fertility by gonadotropin-releasing hormone neurons. Nat Rev Endocrinol. May 20.
Review. View abstract

Grattan DR, Akopian AN. (2016) Oscillating from Neurosecretion to Multitasking Dopamine Neurons. Cell Rep. Apr 26;15(4):681-2. View article

Prescott SL, Allen K, Armstrong K, Collins C, Dickinson H, Gardiner K, Jacka F, Jasoni C, Moore T, Moritz KM, Muhlhausler B, Siero W, Sim K,
Nanan R, Saffery R, Singh G, Vickers MH, Craig JM. (2016) The establishment of DOHaD working groups in Australia and New Zealand. J Dev Orig Health Dis. Apr 27:1-7. View abstract

Kim DW, Glendining KA, Grattan DR, Jasoni CL.(2016) Maternal obesity in the mouse compromises the blood-brain barrier in the arcuate nucleus of offspring. Endocrinology. Apr 7:en20161014. View abstract

Brown CH, Bosch OJ. (2016) Vasopressin and Oxytocin: Conductors of the Symphony of Physiology and Behaviour. J Neuroendocrinol. Apr;28(4). View article

Kim JS, Rizwan MZ, Clegg DJ, Anderson GM. (2016) Leptin Signaling Is Not Required for Anorexigenic Estradiol Effects in Female Mice. Endocrinology. May;157(5):1991-2001. View abstract

Murray LM, Nock V, Evans JJ, Alkaisi MM. (2016) The use of substrate materials and topography to modify growth patterns and rates of differentiation of muscle cells. J Biomed Mater Res A. Jul;104(7):1638-45. View abstract

Kwakowsky A, Potapov K, Kim S, Peppercorn K, Tate WP, Ábrahám IM. (2016) Treatment of beta amyloid 1-42 (Aβ(1-42))-induced basal forebrain cholinergic damage by a non-classical estrogen signaling activator in vivo. Sci Rep. Feb 16;6:21101. View abstract

Decourt C, Anger K, Robert V, Lomet D, Bartzen-Sprauer J, Caraty A, Dufourny L, Anderson G, Beltramo M. (2016) No evidence that RFamide related peptide 3 directly modulates LH secretion in the ewe. Endocrinology. View abstract

Clarkson J, Herbison AE. Hypothalamic control of the male neonatal testosterone surge. (2016) Philos Trans R Soc Lond B Biol Sci. 371(1688). View abstract

Helfer G, Tups A. Hypothalamic Wnt signalling and its role in energy balance regulation. (2016) J Neuroendocrinol. View abstract

Cimino I, Casoni F, Liu X, Messina A, Parkash J, Jamin SP, Catteau-Jonard S, Collier F, Baroncini M, Dewailly D, Pigny P, Prescott M, Campbell R, Herbison AE, Prevot V, Giacobini P. (2016) Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion. Nat Commun. 7:10055. View abstract

Zuure WA, Quennell JH, Anderson GM. (2015) Leptin Responsive and GABAergic Projections to the Rostral Preoptic Area in Mice. J Neuroendocrinol. [Epub ahead of print]. View abstract

Royo JM, Brown CH, Leng G, MacGregor DJ. (2016) Oxytocin Neurones: Intrinsic Mechanisms Governing the Regularity of Spiking Activity. J Neuroendocrinol. Apr;28(4) View abstract

Augustine RA, Bouwer GT, Seymour AJ, Grattan DR, Brown CH. (2016) Reproductive regulation of gene expression in the hypothalamic supraoptic and paraventricular nuclei. J Neuroendocrinol. Apr;28(4) View abstract

Iremonger KJ, Bains JS. (2015) Asynchronous presynaptic glutamate release enhances neuronal excitability during the post-spike refractory period. J Physiol. 594(4):1005-15. View abstract

Boucsein A, Benzler J, Hempp C, Stöhr S, Helfer G, Tups A (2015).  Photoperiodic and diurnal regulation of WNT signalling in the arcuate nucleus of the female Djungarian hamster, Phodopus sungorus. Endocrinology 157(2):799-809. View abstract

Ladyman SR, Augustine RA, Scherf E, Phillipps HR, Brown CH, Grattan DR (2016) Attenuated hypothalamic responses to alpha-melanocyte stimulating hormone during pregnancy in the rat. J Physiol. 594.4 (2016) pp 1087–1101.  View abstract    

Moore AM, Campbell RE. The neuroendocrine genesis of polycystic ovary syndrome: A role for arcuate nucleus GABA neurons. J Steroid Biochem Mol Biol. S0960-0760(15)30104-7. View abstract

Brown RS, Wyatt AK, Herbison RE, Knowles PJ, Ladyman SR, Binart N, Banks WA, Grattan DR (2015) Prolactin transport into mouse brain is independent of prolactin receptor. FASEB J. 30(2):1002-10.  View abstract


Moore AM, Prescott M, Marshall CJ, Yip SH, Campbell RE (2015) Enhancement of a robust arcuate GABAergic input to gonadotropin-releasing hormone neurons in a model of polycystic ovarian syndrome. Proc Natl Acad Sci112(2):596-601. View abstract

CNE Best Paper of the Year 2015

Cheong RY, Czieselsky K, Porteous R, Herbison AE (2015) Expression of ESR1 in Glutamatergic and GABAergic Neurons Is Essential for Normal Puberty Onset, Estrogen Feedback, and Fertility in Female Mice. J. Neurosci. 35(43):14533–14543. View abstract

Evans MC, Rizwan MZ, Anderson GM (2015) Insulin Does Not Target CamkIIα Neurones to Critically Regulate the Neuroendocrine Reproductive Axis in Mice. J. Neuroendocrinology 27(12):899-910. View abstract

Han SY, McLennan T, Czieselsky K, Herbison AE (2015) Selective Optogenetic activation of arcuate kisspeptin neurons generates pulsatile luteinizing hormone secretion. Proc Natl Acad Sci 112(42):13109-14. View abstract

Tan LH, Sykes PH, Alkaisi MM, Evans JJ. (2015) The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface. Int J Nanomedicine 10:4883-95. View abstract

M. Moaddab, B.I. Hyland & C.H. Brown (2015) Oxytocin excites nucleus accumbens shell neurons in vivo. Mol. Cell. Neurosci. 68, 323–330. View abstract

Han SY, Bouwer GT, Seymour AJ, Korpal AK, Schwenke DO, Brown CH (2015) Induction of hypertension blunts baroreflex inhibition of vasopressin neurons in the rat.  European Journal of Neuroscience 42(9):2690-8. View abstract

Herde MK, Herbison AE. (2015) Morphological Characterization of the Action Potential Initiation Segment in GnRH Neuron Dendrites and Axons of Male Mice. Endocrinology 156(11):4174-86. View abstract

Kim JS, Brownjohn PW, Dyer BS, Beltramo M, Walker CS, Hay DL, Painter GF, Tyndall JD, Anderson GM (2015) Anxiogenic and Stressor Effects of the Hypothalamic Neuropeptide RFRP-3 are Overcome by a Novel Antagonist. Endocrinology 156 (11), 4152-4162. View abstract

Hogg SJ, Evans JJ, Sykes PH, Chitcholtan K. (2015) A method to investigate the anti-metabolic activity of anti-cancer agents on ovarian cancer cells cultured in a 96-well high throughput format. J Ovarian Res. 4;8:43. View abstract

Brown RS, Herbison AE, Grattan DR. (2015) Effects of Prolactin and Lactation on A15 Dopamine Neurones in the Rostral Preoptic Area of Female Mice. J Neuroendocrinol. 27(9):708-17. View abstract

David R Grattan (2015) 60 YEARS OF NEUROENDOCRINOLOGY. The hypothalamo-prolactin axis.  Thematic Review. Journal of Endocrinology 226, T101–T122 View abstract

Piet R, Fraissenon A, Boehm U, and Herbison AE (2015) Estrogen Permits Vasopressin Signaling in Preoptic Kisspeptin Neurons in the Female Mouse.  Journal of Neuroscience 35(17):6881-92.   View abstract

Yip SH, Boehm U, Herbison AE, Campbell RE (2015) Conditional viral tract-tracing delineates the projections of the distinct kisspeptin neuron populations to gonadotropin-releasing hormone (GnRH) neurons in the mouse.  Endocrinology 156(7):2582-94. View abstract

Mutreja I, Woodfield TB, Sperling S, Nock V, Evans JJ, Alkaisi MM. (2015) Positive and negative bioimprinted polymeric substrates: new platforms for cell culture. Biofabrication. 7(2):025002. View abstract

Liu X, Herbison AE (2015) Kisspeptin Regulation of Arcuate Neuron Excitability in Kisspeptin Receptor knockout Mice.  Endocrinology 156(5):1815-27. View abstract

Jasoni CL, Sanders TR, Kim DW. (2015) Do all roads lead to Rome? The role of neuro-immune interactions before birth in the programming of offspring obesity. Front Neurosci. 8:455. View abstract

Benzler J, Ganjam GK, Pretz D, Oelkrug R, Koch CE, Legler K, Stöhr S, Culmsee C, Williams LM, Tups (2015) Central inhibition of IKKβ/NF-κB signalling attenuates high fat diet-induced obesity and glucose intolerance. Diabetes. 64(6):2015-27. View abstract

Choe KY, Han SY, Gaub P, Shell B, Voisin DL, Knapp BA, Barker PA, Brown CH, Cunningham JT, Bourque CW. (2015) High salt intake increases blood pressure via BDNF-mediated downregulation of KCC2 and impaired baroreflex inhibition of vasopressin neurons. Neuron. 85(3):549-60. View abstract

Moaddab M, Hyland BI, Brown CH (2015) Oxytocin enhances the expression of morphine-induced conditioned place preference in rats. Psychoneuroendocrinology. 53:159-69. View abstract

Hale MW, Spencer SJ, Conti B, Jasoni CL, Kent S, Radler ME, Reyes TM, Sominsky L. (2015) Diet, behavior and immunity across the lifespan. Neurosci Biobehav Rev. 58:46-62. View abstract

Milne MR, Haug CA, Ábrahám IM, Kwakowsky A. (2015) Estradiol modulation of neurotrophin receptor expression in female mouse basal forebrain cholinergic neurons in vivo. Endocrinology. 156(2):613-26. View abstract

Iremonger KJ, Herbison AE (2015) Multitasking in Gonadotropin-Releasing Hormone Neuron Dendrites. Neuroendocrinology 102(1-2):1-7. View abstract

Piet R, de Croft S, Liu  X, Herbison AE (2015) Electrical properties of kisspeptin neurons and their regulation of GnRH neurons. [review] Frontiers in Neuroendocrinology 36:15-27. View abstract



Campos P and Herbison A.E.  Optogenetic activation of GnRH neurons reveals minimal requirements for pulsatile luteinizing hormone secretion. Proc Natl Acad Sci 111(51):18387-92. View abstract

CNE Best Paper of the Year 2014

Katrina Y. Choe, Su Y. Han, Perrine Gaub, Brent Shell, Daniel L. Voisin, Blayne A. Knapp, Philip A. Barker, Colin H. Brown, J. Thomas Cunningham, and Charles W. Bourque. High Salt Intake Increases Blood Pressure via BDNF-mediated Downregulation of KCC2 and Impaired Baroreflex Inhibition of Vasopressin Neurons. Neuron View abstract

Rizwan MZ, Harbid AA, Inglis MA, Quennell JH, Anderson GM. Evidence that hypothalamic RFamide related peptide-3 neurones are not leptin-responsive in mice and rats. J Neuroendocrinol. 2014 Apr;26(4):247-57. doi: 10.1111/jne.12140. View abstract

Evans GE, Martínez-Conejero JA, Phillipson GT, Sykes PH, Sin IL, Lam EY, Print CG, Horcajadas JA, Evans JJ. In the secretory endometria of women, luminal epithelia exhibit gene and protein expressions that differ from those of glandular epithelia. Fertil Steril. 2014 Jul;102(1):307-317.e7. doi: 10.1016/j.fertnstert.2014.04.005. Epub 2014 May 13. View abstract

Piet R, de Croft S, Liu X, Herbison AE. Electrical properties of kisspeptin neurons and their regulation of GnRH neurons. Front Neuroendocrinol. 2014 Jun 5. pii: S0091-3022(14)00053-3. doi: 10.1016/j.yfrne.2014.05.006. [Epub ahead of print] Review. View abstract

Evans MC, Rizwan MZ, Anderson GM. Insulin action on GABA neurons is a critical regulator of energy balance but not fertility in mice.
Endocrinology 2014 Nov;155(11):4368-79. doi: 10.1210/en.2014-1412. Epub 2014 Aug 13. View abstract

Booker CS, Grattan DR. Identification of a truncated splice variant of IL-18 receptor alpha in the human and rat, with evidence of wider evolutionary conservation. PeerJ 2014 Sep 11;2:e560. doi: 10.7717/peerj.560. eCollection 2014. View abstract

Yeo SH, Clarkson J, Herbison AE. Kisspeptin-gpr54 signaling at the GnRH neuron is necessary for negative feedback regulation of luteinizing hormone secretion in female mice. Neuroendocrinology 2014;100(2-3):191-7. doi: 10.1159/000368608. Epub 2014 Dec 18. View abstract

Clarkson J, Busby ER, Kirilov M, Schütz G, Sherwood NM, Herbison AE. Sexual differentiation of the brain requires perinatal kisspeptin-GnRH neuron signaling. J Neurosci. 2014 Nov 12;34(46):15297-305. doi: 10.1523/JNEUROSCI.3061-14.2014. View abstract

Milne MR, Haug CA, Ábrahám IM, Kwakowsky A. Estradiol modulation of neurotrophin receptor expression in female mouse basal forebrain cholinergic neurons in vivo. Endocrinology 2015 Feb;156(2):613-26. doi: 10.1210/en.2014-1669. Epub 2014 Nov 21. View abstract

Hale MW, Spencer SJ, Conti B, Jasoni CL, Kent S, Radler ME, Reyes TM, Sominsky L. Diet, behavior and immunity across the lifespan. Neurosci Biobehav Rev. 2014 Dec 15. pii: S0149-7634(14)00346-7. doi: 10.1016/j.neubiorev.2014.12.009. [Epub ahead of print] Review. View abstract

Liu X, and Herbison AE.  RF9 excitation of GnRH neurons is dependent upon Kiss1r in the adult male and female mouse.  Endocrinology2014 Dec;155(12):4915-24. doi: 10.1210/en.2014-1517. Epub 2014 Oct 16. View abstract

Evans MC, Rizwan M, Mayer , U. Boehm and G. M. Anderson.  Evidence that insulin signalling in gonadotrophin-releasing hormone and kisspeptin neurones does not play an essential role in metabolic regulation of fertility in mice. Journal of Neuroendocrinology 2014 Jul;26(7):468-79. doi: 10.1111/jne.12166. View abstract

Kim DW, Young SL, Grattan DR, Jasoni CL. Obesity during pregnancy disrupts placental morphology, cell proliferation, and inflammation in a sex-specific manner across gestation in the mouse. Biol Reprod. 2014 Jun;90(6):130. doi: 10.1095/biolreprod.113.117259. Epub 2014 May 14. View article

Campbell RE, Herbison AE. Gonadal steroid neuromodulation of developing and mature hypothalamic neuronal networks. Current Opinion in Neurobiology 2014 Dec;29:96-102. doi: 10.1016/j.conb.2014.06.003. Epub 2014 Jul 1. View abstract

Sanders TR, Kim DW, Glendining KA, Jasoni CL.  Maternal obesity and IL-6 lead to aberrant developmental gene expression and deregulated neurite growth in the fetal arcuate nucleus.  Endocrinology2014 Jul;155(7):2566-77. doi: 10.1210/en.2013-1968. Epub 2014 Apr 28. View abstract

Yeo SH, Herbison AE.  Estrogen-negative feedback and estrous cyclicity are critically dependent upon estrogen receptor-expression in the arcuate nucleus of adult female mice.  Endocrinology 2014 Aug;155(8):2986-95. doi: 10.1210/en.2014-1128. Epub 2014 Jun 6. View_abstract

Kwakowsky, A., Cheong, R.Y., Herbison, A.E., & Ábrahám, I.M (2014) Non-classical effects of estradiol of cAMP responsive element binding protein phosphorylation in gonadotropin-releasing hormone neurons: Mechanisms and role.  Frontiers in Neuroendocrinology 2014 Jan;35(1):31-41. doi: 10.1016/j.yfrne.2013.08.002. Epub 2013 Aug 23. Review. View abstract

Liu X,, R.S.E. Brown RSE, Herbison AE, Grattan DR. Lactational anovulation in mice results from a selective loss of kisspeptin input to GnRH neurons. Endocrinology 2014 Jan;155(1):193-203. doi: 10.1210/en.2013-1621. Epub 2013 Dec 20. Erratum in: Endocrinology. 2014 Apr;155(4):1566. View abstract

Shin J, Prescott M, Mair J, Campbell RE. Roles for primary cilia in gonadotrophin-releasing hormone neurones in the mouse. J Neuroendocrinol. 2014 Jan;26(1):18-25. doi: 10.1111/jne.12122. View abstract

Joe N, Scott V, Brown CH.
Glial regulation of extrasynaptic NMDA receptor-mediated excitation of supraoptic nucleus neurones during dehydration.  J Neuroendocrinol. 2014 Jan;26(1):35-42. doi: 10.1111/jne.12121. View abstract

Cheong RY, Porteous R, Chambon P, Abrahám I, Herbison AE. Effects of neuron-specific estrogen receptor (ER) alpha and ER beta deletion on the acute estrogen negative feedback mechanism in adult female mice.  Endocrinology 2014 Apr;155(4):1418-27. doi: 10.1210/en.2013-1943. Epub 2014 Jan 29. View abstract

Bhattarai JP, Roa J, Herbison AE, Han SK. Serotonin acts through 5-HT1 and 5-HT2 receptors to exert biphasic actions on GnRH neuron excitability in the mouse.  Endocrinology  155(2):513-24. doi: 10.1210/en.2013-1692.  View abstract

Araujo-Lopes R, Crampton JR, Aquino NS, Miranda RM, Kokay IC, Reis AM, Franci CR, Grattan DR, Szawka RE. Prolactin regulates kisspeptin neurons in the arcuate nucleus to suppress LH secretion in female rats.  Endocrinology 2014 Mar;155(3):1010-20. doi: 10.1210/en.2013-1889. View abstract

Brown RC, McLay-Cooke RT, Richardson SL, Williams SM, Grattan DR, Chisholm AWAH.  Appetite response among those susceptible or resistant to obesity.  Int J Endocrinol. 2014;2014:512013. doi: 10.1155/2014/512013. View abstract

Koch CE, Lowe C, Legler K, Benzler J, Boucsein A, Böttiger G, Grattan DR, Williams LM, Tups A.
Central adiponectin acutely improves glucose tolerance in male mice. Endocrinology 2014 May;155(5):1806-16. doi: 10.1210/en.2013-1734. Epub 2014 Feb 24. View abstract



Herde MK, Iremonger KJ, Constantin S, Herbison AE. (2013). GnRH Neurons Elaborate a Long-Range Projection with Shared Axonal and Dendritic Functions. J Neurosci 33(31): 12689-97. doi: 10.1523/JNEUROSCI.0579-13.2013. View abstract

CNE Best Paper of the Year 2013

Wyatt AK, Zavodna M, Viljoen JL, Stanton JL, Gemmell N, and Jasoni CL (2013) Changes in methylation patterns of Kiss1 and Kiss1r gene promoters across puberty. Genetics and Epigenetics, 5: 51-62. doi: 10.4137/GEG.S12897.

Han SY, Gray E, Hughes G, Brown CH, Schwenke DO (2013) Increased sympathetic drive during the onset of hypertension in conscious Cyp1a1-Ren2 rats.  Pflugers Arch – Eur J Physiol doi: 10.1007/s00424-013-1338-5. View abstract

Kwakowsky A, Potapov D, Ábrahám IM (2013) Tracking of single receptor molecule mobility in neuronal membranes: quick theoretical and practical guide. J Neuroendocrinol 25;11;1231-1237 doi: 10.1111/jne.12083. View abstract

Zuure WA, Roberts AL, Quennell JH, Anderson GM (2013) Leptin singaling in GABA neurons, but not glutamate neurons, is required for reproductive function. J Neurosci 33(45):17874-83. doi: 10.1523. View abstract

Iremonger KJ (2013) It takes more than one κ opioid receptor to inhibit a POMC neuron. J Physiol doi:
10.1113/251637. View abstract

Iremonger KJ, Wamsteeker Cusulin JI, Bains JS (2013) Changing the tune: plasticity and adaptation of retrograde signals. Trends in Neuroscience 36, 8, 471-479. View abstract

Steyn, FJ, Wan Y, Veldhuis JD, Herbison AE, Chen C (2013) Development of methodology for, and assessment of pulsatile luteinizing hormone secretion in juvenile and adult male mice. Endocrinology 154, 4939-4945. View abstract

Chen X, Iremonger K, Herbison A, Kirk V, Sneyd J (2013) Regulation of electrical bursting in a spatio-temporal model of a GnRH neuron. Bull Math Biol doi: 10.1007/s11538-013-9877-7. View abstract

De Croft S, Boehm U, Herbison AE (2013) Neurokinin B activates arcuate kisspeptin neurons through multiple tachykinin receptors in the male mouse. Endocrinology 154, 2750-2760. View abstract

Franceschini I, Yeo S, Beltramo M, Desroziers E, Okamura H, Herbison AE, Caraty A (2013) Immunohistochemical evidence for the presence of various kisspeptin isoforms in the mammalian brain. J Neuroendocrinol 839-851. View abstract

Kirilov M, Clarkson J, Liu X, Roa J, Campos P, Porteous R, Schütz G, Herbison AE. (2013). Dependence of fertility on kisspeptin-Gpr54 signaling at the GnRH neuron. Nat Commun 4: 2492. doi: 10.1038/ncomms3492. View abstract

Piet R, Boehm U, Herbison AE. (2013). Estrous cycle plasticity in the hyperpolarization-activated current ih is mediated by circulating 17β-estradiol in preoptic area kisspeptin neurons. J Neurosci 33(26): 10828-39. doi: 10.1523/JNEUROSCI.1021-13.2013. View abstract

Liu X, Herbison AE. (2013). Dopamine Regulation of Gonadotropin-Releasing Hormone Neuron Excitability in Male and Female Mice. Endocrinology 154(1): 340-50. doi: 10.1210/en.2012-1602. View abstract

Romanò N, Yip SH, Hodson DJ, Guillou A, Parnaudeau S, Kirk S, Tronche F, Bonnefont X, Le Tissier P, Bunn SJ, Grattan DR, Mollard P, Martin AO. (2013). Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release. J Neurosci 33(10): 4424-33. doi: 10.1523/JNEUROSCI.4415-12.2013. View abstract

Moore AM, Prescott M, Campbell RE. (2013). Estradiol Negative and Positive Feedback in a Prenatal Androgen-Induced Mouse Model of Polycystic Ovarian Syndrome. Endocrinology 154(2): 796-806. doi: 10.1210/en.2012-1954. View abstract

Harbid AA, McLeod BJ, Caraty A, Anderson G. (2013.) Seasonal changes in RFamide-related peptide-3 neurons in the hypothalamus of a seasonally breeding marsupial species, the brushtail possum (Trichosurus vulpecula). J Comp Neurol 521(13): 3030-41. doi: 10.1002/cne.23328. View abstract

Singireddy A, Inglis M, Zuure W, Kim J, Anderson G. (2013). Neither signal transducer and activator of transcription 3 (STAT3) or STAT5 signaling pathways are required for leptin's effects on fertility in mice. Endocrinology. 154(7): 2434-45. doi: 10.1210/en.2013-1109. View abstract

Ladyman SR, Grattan DR. (2013). JAK-STAT and feeding. JAKSTAT 2(2): e23675. doi: 10.4161/jkst.23675. View abstract at Landes Bioscience

Bhattarai JP, Ábrahám IM, Han SK. (2013). Genistein Excitation of Gonadotrophin-Releasing Hormone Neurones in Juvenile Female Mice. J Neuroendocrinol 25(5): 497-505. doi: 10.1111/jne.12020. View abstract

Constantin S, Iremonger KJ, Herbison AE. (2013). In Vivo Recordings of GnRH Neuron Firing Reveal Heterogeneity and Dependence upon GABA-A Receptor Signaling. J Neurosci 33(22): 9394-401. doi: 10.1523/JNEUROSCI.0533-13.2013. View abstract

Clarkson J. (2013). Effects of estradiol on kisspeptin neurons during puberty. Front Neuroendocrinol 34(2): 120-31. doi: 10.1016/j.yfrne.2013.02.002. View abstract

Brown CH, Bains JS, Ludwig M, Stern JE. (2013) Physiological Regulation of Magnocellular Neurosecretory Cell Activity: Integration of Intrinsic, Local and Afferent Mechanisms. J Neuroendocrinol 25(8): 678-710. doi: 10.1111/jne.12051. View abstract

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Iremonger K, Herbison AE. (2012). Initiation and propagation of action potentials in gonadotropin-releasing hormone neuron dendrites. J Neurosci, 32, pp. 151-158. View abstract

CNE Best Paper of the Year 2012

Low VF, Fiorini Z, Fisher L, Jasoni CL. (2012). Netrin-1 stimulates developing GnRH neurons to extend neurites to the median eminence in a calcium- dependent manner. PLoS One 7(10): e46999. View abstract

Chitcholtan K, Sykes PH, and Evans JJ. (2012). The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer. J Transl Med 10: 38. View abstract

Evans GE, Martinez-Conejero JA, Phillipson GT, Simon C, McNoe LA, Sykes PH, Horcajadas JA, Lam EY, Print CG, Sin IL, and Evans JJ. (2012). Gene and protein expression signature of endometrial glandular and stromal compartments during the window of implantation. Fertil Steril 97 (6), pp. 1365-73. e1-2. View abstract

Evans GE, Phillipson GT, Sin IL, Frampton CM, Kirker JA, Bigby SM, and Evans JJ. (2012). Gene expression confirms a potentially receptive endometrium identified by histology in fertile women. Hum Reprod 27, pp. 2747-2755. View abstract

Ibrahim SN, Murray L, Evans JJ, and Alkaisi MM. (2012). The Quadrupole Microelectrode Design on a Multilayer Biochip. Microelectronic Engineering 97, pp. 369-374. View abstract at ScienceDirect

Yoshida A, Chitcholtan K, Evans JJ, Nock V, and Beasley SW. (2012). In vitro tissue engineering of smooth muscle sheets with peristalsis using a murine induced pluripotent stem cell line. Journal of Pediatric Surgery 47, pp. 329-335. View abstract at ScienceDirect

Brown RSE, Piet R, Herbison AE, Grattan DR. (2012). Differential actions of prolactin on electrical activity and intracellular signal transduction in hypothalamic neurons. Endocrinology, online. doi: 10.1210/en.2011-2005. View abstract

Constantin S, Jasoni C, Romano N, Lee K, Herbison AE. (2012) Understanding calcium homeostasis in postnatal gonadotropin-releasing hormone neurons using cell-specific Pericam transgenics. Cell Calcium 51, pp. 267-276. View abstract

Panzica GC, Balthazart J, Frye CM, Garcia-Segura LM, Herbison AE, Mensah Nyagam G, McCarthy MM, Melcangi RC. (2012) Milestones on steroids and the nervous system: Ten years of basic and translational research. J Neuroendocrinol 24, pp. 1-15. View abstract

Handa RJ, Ogawa S, Wang JM, Herbison AE. (2012) Roles for estrogen receptor β in adult brain function. J Neuroendocrinol 24, pp. 160-173. View abstract

Clarkson J, Shamas S, Mallinson S, Herbison AE. (2012) Gonadal steroid induction of kisspeptin expression in the rostral periventricular area of the third ventricle during postnatal development in the male mouse. J Neuroendocrinol 24, pp. 907-915. View abstract

Romano N, Herbison AE. (2012) Activity-dependent modulation of GnRH neuron activity by acute estradiol. J Neuroendocrinol 24, pp. 1296-1303. View abstract

Constantin S, Piet R, Iremonger K, Yeo SH, Clarkson J, Porteous R, Herbison AE. (2012) GnRH neuron firing and response to GABA in vitro depends on acute brain slice thickness and orientation. Endocrinology 153, pp. 3758-3769. View abstract

Cheong R, Kwakovsky A, Barad Z, Porteous R, Herbison AE, Ábrahám IA. (2012) Estradiol acts directly and indirectly on multiple signaling pathways to phosphorylate cAMP-response element binding protein in gonadotropin-releasing hormone neurons. Endocrinology 153, pp. 3792-3803. View abstract

Lee K, Liu X, Herbison AE. (2012) Burst firing in gonadotropin-releasing hormone neurons does not require ionotropic GABA or glutamate receptor activation. J Neuroendocrinol 24, pp. 1476-1483. View abstract

Kwakovsky A, Herbison AE, Ábrahám IA. (2012) The role of cAMP response element binding protein in estrogen negative feedback controling gonadotropin-releasing hormone neurons. J Neurosci 32, pp. 11309-11317. View abstract

Roa J, Herbison AE. (2012) Direct regulation of GnRH neuron excitability by arcuate nucleus POMC and NPY neuron neuropeptides in female mice. Endocrinology 153, pp. 5587-5599. View abstract

de Croft S, Piet R, Mayer C, Mai O, Boehm U, Herbison AE. (2012) Spontaneous kisspeptin neuron firing in the adult mouse reveals marked sex and brain region differences but no support for a direct role in negative feedback. Endocrinology 153, pp. 5384-5393. View abstract

Adler E, Hollis J, Clarke I, Grattan DR, and Oldfield B. (2012) Neurochemical characterization and sexual dimorphism of projections from the brain to abdominal and subcutaneous white adipose tissue in the rat. J Neurosci 32 (45), pp. 15913-21. View abstract

Benzler J, Ganjam GK, Krüger M, Pinkenburg O, Kutschke M, Stöhr S, Steger J, Koch CE, Olkrug R, Schwartz MW, Shepherd PR, Grattan DR, Tups A. Hypothalamic glycogen-synthase-kinase 3β has a central role in the regulation of food intake and glucose metabolism. Biochem J 447 (1), pp. 175-84. View abstract

Yip SH, Eguchi R, Grattan DR, Bunn SJ. (2012) Prolactin signalling in the mouse hypothalamus is primarily mediated by signal transducer and activator of transcription factor 5b but not 5a. J Neuroendocrinol 12, pp. 1484-91. View abstract

Ladyman SR, Fieldwick DM, Grattan DR. (2012) Suppression of leptin-induced hypothalamic JAK/STAT signaling and feeding response during pregnancy in the mouse. Reproduction 144 (1), pp. 83-90. View abstract

Li Q, Li N, Le Tissier P, Grattan DR, Kerman, K. (2012) Miniaturized Electrochemical Immunosensor for Label-Free Detection of Growth Hormone. Electroanalysis, 24 (6), pp. 1272-1276. View abstract at

Kőszegi Z, Ábrahám IM. (2012) Effect of ageing on post-lesion oestradiol treatment on mouse cholinergic neurones in vivo. J Neuroendocrinol 24 (9), pp. 1243-1248. View abstract

Rizwan MZ, Poling MC, Cornes PA, Augustine RA, Quennell JH, Kauffman AS, Anderson GM (2012) RFamide-related peptide-3 receptor gene expression on GnRH and kisspeptin neurons and GnRH-dependent mechanism of action. Endocrinology, 153 (8), pp. 3770-9. View abstract

Evans JJ, Anderson GM (2012) Balancing ovulation and anovulation: integration of the reproductive and energy balance axes by neuropeptides. Hum Reprod Update, 18, pp. 313-332. View abstract

de Vries GJ, Veenema AH, Brown CH. (2012). Vasopressin and oxytocin: keys to understanding the neural control of physiology and behaviour. J Neuroendocrinol, 24 (4), pp. 527. View abstract

Sapsford T, Kokay IC, Ostberg L, Bridges RS, Grattan DR. (2012). Differential sensitivity of specific neuronal populations of the rat hypothalamus to prolactin action. J Comp Neurol, 520 (5), pp. 1062-77. View abstract

Larsen CM, Grattan DR. (2012). Prolactin, neurogenesis, and maternal behaviors. Brain Behav Immun, 26 (2), pp. 201-9. View abstract

Tasker JG, Oliet SH, Bains JS, Brown CH, Stern JE. (2012). Glial regulation of neuronal function: from synapse to systems physiology. J Neuroendocrinol, 24 (4), pp. 566-76. View abstract

Evans JJ, Chitcholtan K, Dann JM, Guilford P, Harris G, Lewis LK, Nagase J, Welkamp AAW, Zwerus R, Sykes PH. (2012). Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecol Oncol, 125 (1), pp. 214-9. View abstract

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Liu X, Petersen S, d'Anglemont de Tassigny X, Colledge WH, Herbison AE. (2011). Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neurons excitability. J Neurosci, 31, pp. 2421-2430. View abstract

CNE Best Paper of the Year 2011

Ladyman SR, Sapsford TJ, Grattan DR. (2011). Loss of acute satiety response to cholecystokinin in pregnant rats. J Neuroendocrinol, 23, pp. 1091-8. View abstract

Bhattarai JP, Park SA, Park JB, Lee SY, Herbison AE, Ryu PD, Han SK. (2011). Tonic extrasynaptic GABA A receptor currents control gonadotropin-releasing hormone neuron excitability in the mouse. Endocrinology, 152, pp. 1551-1561. View abstract

Herbison AE, Moenter SM. (2011). Depolarizing and hyperpolarizing actions of GABA A receptor activation on GnRH neurons: towards an emerging consensus. J Neuroendocrinol, 23, pp. 557-569. View abstract

Porteous R, Petersen SL, Yeo SH, Ciofi P, d'Anglemont de Tassigny X, Colledge WH, Caraty A, Herbison AE. (2011). Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular area of the female mouse. J Comp Neurol, 519, pp. 3456-3469. View abstract

Herde M, Geist K, Campbell RE, Herbison AE. (2011). Gonadotropin-releasing hormone neurons extend complex dendritic trees outside the blood-brain barrier. Endocrinology, 152, pp. 3832-3841. View abstract

Liu X, Herbison AE. (2011). Estrous cycle- and sex-dependent changes in pre- and post-synaptic GABA B control of gonadotropin-releasing hormone neuron excitability. Endocrinology, 152, pp. 4856-4864. View abstract

Chan H, Prestcott M, Ong ZY, Herbison AE, Campbell RE. (2011). Dendritic spine plasticity in gonadatropin-releasing hormone (GnRH) neurons activated at the time of the pre-ovulatory surge. Endocrinology, 152, pp. 4906-4914. View abstract

Scott V & Brown CH. (2011). Kisspeptin activation of supraoptic nucleus neurons in vivo. Endocrinology, 152, pp. 3862-3870. View abstract

Fleming TM, Scott V, Joe N, Naskar K, Brown CH, Stern JE. (2011). State-dependent changes in astrocyte regulation of extrasynaptic NMDA receptor signalling in neurosecretory neurons. J Physiol, 589 (Pt 16), pp. 3929-41. View abstract

Bull PM, Russell JA, Scott V, Brown CH. (2011). Apamin increases post-spike excitability of supraoptic nucleus neurons in anaesthetized morphine naïve rats and morphine dependent rats: consequences for morphine withdrawal excitation. Exp Brain Res, 212, pp. 517-528. View abstract

Ruan M, Russell JA, Brown CH. (2011). Acute morphine administration and withdrawal from chronic morphine increase afterdepolarization amplitude in rat supraoptic nucleus neurons in hypothalamic explants. Neuropharmacology, 61, pp. 789-797. View abstract

Koszegi Zs, Szegő ÉM, Cheong RY, Tolod-Kemp E, Ábrahám IM. (2011). Post-lesion Estradiol Treatment Increases Cortical Cholinergic Innervations via Estrogen Receptor Alpha Dependent Non-classical Estrogen Signaling in vivo. Endocrinology, 152 (9), pp. 3471-82. View abstract

Constantin S. (2011). Physiology of the Gonadotrophin-Releasing Hormone (GnRH) Neurone: Studies from Embryonic GnRH Neurones. J Neuroendocrinol, 23 (6), pp. 542-553. View abstract

Sjoeholm A, Bridges RS, Grattan DR, Anderson GM. (2011). Region-, Neuron-, and Signaling Pathway-Specific Increases in Prolactin Responsiveness in Reproductively Experienced Female Rats. Endocrinology, 152 (5), pp. 1979-1988. View abstract

Campbell RE, Ducret E, Porteous R, Liu X, Herde MK, Wellerhaus K, Sonntag S, Willecke K, Herbison AE. (2011). Gap Junctions between Neuronal Inputs But Not Gonadotropin-Releasing Hormone Neurons Control Estrous Cycles in the Mouse. Endocrinology, 152 (6). pp. 2290-2301. View abstract

Yeo S-H, Herbison AE. (2011). Projections of Arcuate Nucleus and Rostral Periventricular Kisspeptin Neurons in the Adult Female Mouse Brain. Endocrinology, 152 (6), pp. 2387-99. View abstract

Knowles PJ, Douglas SA, Bunn SJ. (2011). Nicotinic stimulation of catecholamine synthesis and tyrosine hydroxylase phosphorylation in cervine adrenal medullary chromaffin cells. J Neuroendocrinol, 23, pp. 224-231. View abstract

Quennell JH, Howell CS, Roa J, Augustine RA, Grattan DR, Anderson GM. (2011). Leptin Deficiency and Diet-Induced Obesity Reduce Hypothalamic Kisspeptin Expression in Mice. Endocrinology, 152 (4), pp. 1541-1550. View abstract

Clarkson J, Herbison AE. (2011). Dual phenotype kisspeptin-dopamine neurones of the rostral periventricular area of the third ventricle project to GnRH neurones. J Neuroendocrinol, 23, (4), pp. 293-301. View abstract

Brown RSE, Herbison AE, Grattan DR. (2011). Differential changes in responses of hypothalamic and brainstem neuronal populations to prolactin during lactation in the mouse. Biol Reprod, 84, (4), pp. 26-36. View abstract

Kokay IC, Petersen SL, Grattan DR. (2011). Identification of prolactin-sensitive GABA and Kisspeptin neurons in regions of the rat hypothalamus involved in the control of fertility. Endocrinology, 152, (2), pp. 526-35. View abstract

Szegő EM, Csorba A, Janáky T, Kékesi KA, Ábrahám IM, Mórotz GM, Penke B, Palkovits M, Murvai U, Kellermayer MSZ, Kardos J, Juhász GD. (2011). Effects of Estrogen on Beta-Amyloid-Induced Cholinergic Cell Death in the Nucleus Basalis Magnocellularis. Neuroendocrinology, 93 (2), pp. 90-105. View abstract

Phillips HR, Kokay IC, Grattan DR, Hurst PR. (2011). X-linked inhibitor of apoptosis protein (XIAP) and active caspase-3 expression patterns in antral follicles in the sheep ovary. Reproduction, 142, pp. 855-67. View abstract

Anderson GM. (2011). Pituitary actions of RFamide peptides: a critique of the evidence. Open Neuroendocrinol J, 4, pp. 51-63. View abstract

Duan W, Lee K, Herbison AE, Sneyd J. (2011). A mathematical model of adult GnRH neurons in mouse brain and its bifurcation analysis. J Theor Biol 276, pp. 22-34. View abstract

Samsuri F, Alkaisi MM, Evans JJ, Chitcholtan K, Mitchell JS. (2011). Detection of changes in cell membrane structures using the Bioimprint technique. Microelectronic Engineering, 88, (8), pp. 1871–1874. View abstract at ScienceDirect

Nock V, Murray L, Samsuri F, Alkaisi MM, Evans JJ. (2011). Microfluidic arrays for bioimprint of cancer cells. Microelectronic Engineering, 88, (8), pp. 1828–1831. View abstract at ScienceDirect

Ibrahim SN, Murray L, Evans JJ, and M.Alkaisi M. (2011). Trapping single cells: comparison between sandwiched insulation with back contact (SIBC) and planar biochip. Materials Science Forum, 700, pp 188-194. View online at Materials Science Forum

Evans JJ. (2011). The anterior pituitary gland - co-ordinating an alphabet of peptides. Open Neuroendocrinol J, 4, pp. 22-24. View online

Evans JJ, Chitcholtan K. (2011). Extracellular matrix proteins in the anterior pituitary gland. Open Neuroendocrinol J, 4, pp. 111-119. View online

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Larsen CM, Grattan DR. (2010). Prolactin-induced mitogenesis in subventricular zone of the maternal brain during early pregnancy is essential for normal postpartum behavioral responses in the mother. Endocrinology, 151, pp. 3805-3814. View abstract

CNE Best Paper of the Year 2010

Douglas SA, Sreenivasan D, Carman FH, Bunn SJ. (2010). Cytokine interactions with adrenal medullary chromaffin cells. Cell Mol Neurobiol, 30, pp. 1467-1475. View abstract

Koch C, Augustine RA, Steger J, Ganjam CK, Benzler J, Pracht C, Lowe C, Schwartz MW, Shepherd PR, Anderson GM, Grattan DR, Tups A. (2010). Leptin Rapidly Improves Glucose Homeostasis in Obese Mice by Increasing Hypothalamic Insulin Sensitivity. J Neurosci, 30 (48), pp. 16180-16187. View abstract

Fiorini Z, Jasoni CL. A novel developmental role for Kisspeptin in the growth of GnRH neurites to the median eminence in the mouse. J Neuroendocrinol, 22 (10), pp. 1113-25. View abstract

Campbell RE, Suter KJ. (2010). Redefining the gonadotrophin-releasing hormone neurone dendrite. J Neuroendocrinol, 22 (7), pp. 650-8. View abstract

Lee K, Porteous R, Campbell RE, Lüscher B, Herbison AE. (2010). Knockdown of GABA(A) Receptor Signaling in GnRH Neurons Has Minimal Effects upon Fertility. Endocrinology, 151 (9), pp. 4428-36. View abstract

Szawka RE, Ribeiro AB, Leite CM, Helena CV, Franci CR, Anderson GM, Hoffman GE, Anselmo-Franci JA. (2010). Kisspeptin Regulates Prolactin Release through Hypothalamic Dopaminergic Neurons. Endocrinology, 151 (7), pp. 3247-3257. View abstract

Tups A, Anderson GM, Rizwan M, Augustine RA, Chaussade C, Shepherd PR, Grattan DR. (2010). Both p110alpha and p110beta isoforms of phosphatidylinositol 3-OH-kinase are required for insulin signalling in the hypothalamus. J Neuroendocrinol, 22 (6), pp 534-42. View abstract

Quennell JH, Rizwan MZ, Relf H-L, Anderson GM. (2010). Developmental and Steroidogenic Effects on the Gene Expression of RFamide Related Peptides and their Receptor in the Rat Brain and Pituitary Gland. J Neuroendocrinol, 22 (4), pp. 309-316. View abstract

Herbison AE, d'Anglemont de Tassigny X, Colledge WH. (2010). Distribution and development of Gpr54 expression in mouse brain and gonadotropin-releasing hormone neurons. Endocrinology, 151, pp. 312-321. View abstract

Constantin S, Jasoni CL, Wadas B, Herbison AE. (2010). GABA and glutamate differentially regulate intracellular calcium concentrations in mouse GnRH neurons. Endocrinology, 151 (1), pp. 262-270. View abstract

Scott V, Brown CH. (2010). State-dependent plasticity in vasopressin neurones: dehydration-induced changes inactivity patterning. J Neuroendocrinol, 22 (5), pp. 343-54. View abstract

Adori M, Kiss E, Barad Z, Barabás K, Kiszely E, Schneider A, Sziksz E, Ábrahám I, Matko J, Sarmay G. (2010). Estrogen augments the T cell-dependent but not the T-independent immune response. Cell Mol Life Sci, 67 (10), pp. 1661-74. View abstract

Brown RS, Kokay IC, Herbison AE, Grattan DR. (2010). Distribution of prolactin-responsive neurons in the mouse forebrain. J Comp Neurol, 518 (1), pp. 92-102. View abstract

Han SK, Lee K, Bhattarai JP, Herbison AE. (2010). Gonadotrophin-releasing hormone (GnRH) exerts stimulatory effects on GnRH neurons in intact adult male and female mice. J Neuroendocrinol, 22, pp. 188-195. View abstract

Igelstrom KM, Herbison AE, Hyland BI. (2010). Enhanced c-Fos expression in superior colliculus, paraventricular thalamus and septum during learning of cue-reward association. Neuroscience, 168, pp. 706-714. View abstract

Clarkson J, Han S-K, Liu X, Lee K, Herbison AE. (2010). Neurobiological mechanisms underlying kisspeptin activation of gonadotropin-releasing hormone (GnRH) neurons at puberty. Mol Cell Endocrinol, 324, pp. 45-50. View abstract

Ducret E, Gaidamaka G, Herbison AE. (2010). Electrical and morphological characteristics of anteroventral periventricular nucleus kisspeptin and other neurons in the female mouse. Endocrinology, 151, pp. 2223-2232. View abstract

Lee K, Duan W, Sneyd J, Herbison AE. (2010). Two slow calcium-activated afterhyperpolarization currents control burst firing dynamics in gonadotropin-releasing hormone neurons. J Neurosci, 30, pp. 6214-6224. View abstract

Bhattarai JP, Kaszás A, Park SA, Yin H, Park SJ, Herbison AE, Han SK, Ábrahám IM. (2010). Somatostatin inhibition of gonadotropin-releasing hormone neurons in male and female mice. Endocrinology, 151, pp. 3258-3266. View abstract

Jasoni CL, Romano N, Constantin S, Lee K, Herbison AE. (2010). Calcium dynamics in gonadotropin-releasing hormone neurons. Front Neuroendocrinol, 31, pp. 259-269. View abstract

Iremonger KJ, Constantin S, Liu X, Herbison AE. (2010). Glutamate regulation of GnRH neuron excitability. Brain Res, 1364, pp. 35-43. View abstract

Brown CH, Oiso Y, Ueta Y. (2010). Vasopressin & oxytocin: focus in the post-genomic era. J Neuroendocrinol, 22, pp. 317. View abstract

Rouet V, Bogorad RL, Kayser C, Kessal K, Genestie C, Bardier A, Grattan DR, Kelder B, Kopchick JJ, Kelly PA, Goffin V. (2010). Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors. Proc Natl Acad Sci U S A, 107 (34), pp. 15199-204. View abstract

Larsen C.M, Grattan DR. (2010). Exposure to female pheromones during pregnancy causes postpartum anxiety in mice. Vitam Horm, 83, pp. 137-149. View abstract

Ladyman SR, Augustine RA, Grattan DR. (2010). Hormone interactions regulating energy balance during pregnancy. J Neuroendocrinol, 22, pp. 805-817. View abstract

Nock V, Murray LM, Samsuri F, Alkaisi MM, Evans JJ. (2010). Microfluidics-assisted photo nanoimprint lithography for the formation of cellular bioimprints. J Vac Sci Technol B, 28 (6), C6K17-C16K22. doi: 10.1116/1.3501342, View abstract at AVS publications

Samsuri F, Alkaisi MM, Mitchell J, Evans JJ. (2010). Replication of Cancer cells using Soft Lithography Bioimprint Technique. Microelectronic Engineering, 87, pp. 699-703. View abstract at ScienceDirect

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Campbell RE, Gaidamaka G, Han SK, Herbison AE. (2009). Dendro-dendritic bundling and shared synapses between gonadotropin-releasing hormone neurons. Proc Natl Acad Sci U S A, 106, pp. 10835-10840. View abstract

CNE Best Paper of the Year 2009

Sárvári M, Szego EM, Barabás K, Jávor A, Tóth S, Kovács Z, Ábrahám IM. (2009). Genistein induces phosphorylation of cAMP response element-binding protein in neonatal hypothalamus in vivo. J Neuroendocrinol, 21, pp. 1024-1028. View abstract

Scott V, Bishop VR, Leng G, Brown CH. (2009). Dehydration-induced modulation of kappa-opioid inhibition of vasopressin neurone activity. J Physiol, 587, pp. 5679-5689. View abstract

Herbison AE. (2009). Rapid actions of oestrogen on gonadotropin-releasing hormone neurons; from fantasy to physiology? J Physiol, 587 (Pt 21), pp. 5025-30. View abstract

Clarkson J, d'Anglemont de Tassigny X, Colledge WH, Caraty A, Herbison AE. (2009). Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain. J Neuroendocrinol, 21, pp. 673-82. View abstract

Ladyman SR, Tups A, Augustine RA, Swahn-Azavedo AM, Kokay IC, Grattan DR. (2009). Loss of hypothalamic response to leptin during pregnancy associated with development of melanocortin resistance. J Neuroendocrinol, 21, pp. 449-456. View abstract

Clarkson J, Boon WC, Simpson ER, Herbison AE. (2009). Postnatal development of an estradiol-kisspeptin positive feedback mechanism implicated in puberty onset. Endocrinology, 150 (7), pp. 3214-3220. View abstract

Samsuri F, Mitchell J, Alkaisi M, Evans J. (2009). Formation of Nanoscale Bioimprints of Muscle Cells using UV Cured Spin Coated Polymers. Journal of Nanotechnology, Article ID: 593410. doi:10.1155/2009/593410 View online

Pearson LJ, Yandle TG, Nicholls MG & Evans JJ. (2009). Intermedin (Adrenomedullin-2): a Potential Protective Role in Human Aortic Endothelial Cells. Cell Physiol Biochem, 23, pp. 97-108. View abstract

Peters EEM, Towler K, Mason DR & Evans JJ. (2009). Effects of Galanin and Leptin on Gonadotropin-Releasing Hormone-Stimulated Luteinising Hormone Release from the Pituitary. Neuroendocrinology, 89, pp. 18-26. View abstract

Quennell JH, Mulligan AC, Tups A, Liu X, Phipps SJ, Kemp CJ, Herbison AE, Grattan DR, Anderson GM. (2009). Leptin indirectly regulates GnRH neuronal function. Endocrinology, 150, pp. 2805-2812. View abstract

Ruan M, Brown C. (2009). Feedback inhibition of action potential discharge by endogenous adenosine enhancement of the medium afterhyperpolarization. J Physiol, 587, pp. 1043-1056. View abstract

Ducret E, Anderson GM, Herbison AE. (2009). RFamide-related peptide-3 (RFRP-3), a mammalian gonadotropin-inhibitory hormone ortholog, regulates gonadotropin-releasing hormone (GnRH) neuron firing in the mouse. Endocrinology, 150, pp. 2799-2804. View abstract

Yang JJ, Larsen CM, Grattan DR, Erskine MS. (2009). Mating-induced neuroendocrine responses during pseudopregnancy in the female mouse. J Neuroendocrinol, 21 (1), pp. 30-9. View abstract

Rizwan MZ, Porteous R, Herbison AE, Anderson GM. (2009). Cells expressing RFRP-1/3, the mammalian GnIH orthologs, are not hypophysiotropic neuroendocrine neurons in the rat. Endocrinology, 150 (3), pp. 1413-20. View abstract

Clarkson J, Herbison AE. (2009). Oestrogen, Kisspeptin, GPR54 and the Preovulatory Luteinising Hormone Surge. J Neuroendocrinol, 21 (4), pp. 305-11. View abstract

Jasoni CL, Porteous RW, Herbison AE. (2009). Anatomical location of mature GnRH neurons corresponds with their birthdate in the developing mouse. Dev Dyn, 238 (3), pp. 524-531. View abstract

Anderson GM, Relf HL, Rizwan MZ, Evans JJ. (2009). Central and peripheral effects of RFamide-related peptide-3 on LH and prolactin secretion in rats. Endocrinology, 150 (4), pp. 1834-30. View abstract

Peters EEM, Towler K, Mason DR, Evans JJ. (2009). Effects of galanin and leptin on gonadotropin-releasing hormone-stimulated luteinising hormone release from the pituitary. Neuroendocrinology, 89 (1), pp. 18-26. View abstract

Alkaisi MM, Muys JJ & Evans JJ. (2009). Single cell imaging with AFM using Biochip/Bioimprint technology International Journal of Nanotechnology, 6, pp. 355-368. View abstract at Inderscience Publishers

Ábrahám IM, Koszegi Z, Tolod-Kemp E, Szego EM. (2009). Action of estrogen on survival of basal forebrain cholinergic neurons: promoting amelioration. Psychoneuroendocrinology, 34, pp. 104-12. View abstract

Dann JM, Evans JJ, Mason DR & Sykes PH. (2009). Regulation of Vascular Endothelial Growth Factor in Endometrial Tumour Cells by Resveratrol and EGCG. Gynecol Oncol, 113, pp. 374-8. View abstract

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Romano, N., Lee, K., Ábrahám, I.M., Jasoni, C.L., Herbison, A.E. Nonclassical estrogen modulation of presynaptic GABA terminals modulates calcium dynamics in gonadotropin-releasing hormone neurons. (2008) Endocrinology, 149 (11), pp. 5335-5344.
DOI: 10.1210/en.2008-0424 View abstract

CNE Best Paper of the Year 2008

Douglas, S.A., Stevenson, K.E., Knowles, P.J., Bunn, S.J. Characterization of catecholamine release from deer adrenal medullary chromaffin cells. (2008). Neurosci Let, 445 (1), pp. 126-129. DOI: 10.1016/j.neulet.2008.08.060 View abstract

Grattan, D.R. Fetal programming from maternal obesity: Eating too much for two? (2008). Endocrinology, 149 (11), pp. 5345-5347. DOI: 10.1210/en.2008-1106 View abstract

Kwakowsky, A., Schwirtlich, M., Kooy, F., Ábrahám, I., Máté, Z., Katarova , Z., and Szabó, G. GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. (2008). Dev Dyn, 237:3830-41. DOI: 10.1002/dvdy.21768 View abstract

Leng, G., Brown, C., Sabatier, N., Scott, V. Population dynamics in vasopressin cells. (2008). Neuroendocrinology, 88 (3), pp. 160-172. DOI: 10.1159/000149827 View abstract

Liu, X., Lee, K., Herbison, A.E. Kisspeptin excites gonadotropin-releasing hormone neurons through a phospholipase C/calcium-dependent pathway regulating multiple ion channels. (2008). Endocrinology, 149 (9), pp. 4605-4614. DOI: 10.1210/en.2008-0321 View abstract

Clarkson, J., d'Anglemont de Tassigny, X., Moreno, A.S., Colledge, W.H., Herbison, A.E. Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. (2008). J Neurosci, 28 (35), pp. 8691-8697. DOI: 10.1523/JNEUROSCI.1775-08.2008 View abstract

Brown, C.H., Ruan, M., Scott, V., Tobin, V.A., Ludwig, M. Multi-factorial somato-dendritic regulation of phasic spike discharge in vasopressin neurons. (2008). Prog Brain Res, 170, pp. 219-228. DOI: 10.1016/S0079-6123(08)00419-6 View abstract

Liu, X., Herbison, A.E. Small-conductance calcium-activated potassium channels control excitability and firing dynamics in Gonadotropin-Releasing Hormone (GnRH) neurons. (2008) . Endocrinology, 149 (7), pp. 3598-3604. DOI: 10.1210/en.2007-1631 View abstract

Roberts, C.B., Campbell, R.E., Herbison, A.E., Suter, K.J. Dendritic action potential initiation in hypothalamic gonadotropin- releasing hormone neurons. (2008). Endocrinology, 149 (7), pp. 3355-3360. DOI: 10.1210/en.2008-0152 View abstract

Grattan, D.R., Kokay, I.C. Prolactin: A pleiotropic neuroendocrine hormone. (2008). J Neuroendocrinol, 20 (6), pp. 752-763. DOI: 10.1111/j.1365-2826.2008.01736.x View abstract

Steyn, F.J., Anderson, G.M., Grattan, D.R. Hormonal regulation of suppressors of cytokine signaling (SOCS) messenger ribonucleic acid in the arcuate nucleus during late pregnancy. (2008). Endocrinology, 149 (6), pp. 3206-3214. DOI: 10.1210/en.2007-1623 View abstract

Pearson, L.J., Yandle, T.G., Nicholls, M.G., Evans, J.J. Regulation of endothelin-1 release from human endothelial cells by sex steroids and angiotensin-II. (2008). Peptides, 29 (6), pp. 1057-1061. DOI: 10.1016/j.peptides.2008.02.003 View abstract

Anderson, G.M., Kieser, D.C., Steyn, F.J., Grattan, D.R. Hypothalamic prolactin receptor messenger ribonucleic acid levels, prolactin signaling, and hyperprolactinemic inhibition of pulsatile luteinizing hormone secretion are dependent on estradiol. (2008). Endocrinology, 149 (4), pp. 1562-1570. DOI: 10.1210/en.2007-0867 View abstract

Brown, C.H., Brunton, P.J., Russell, J.A. Rapid estradiol-17β modulation of opioid actions on the electrical and secretory activity of rat oxytocin neurons in vivo. (2008). Neurochem Res, 33 (4), pp. 614-623. DOI: 10.1007/s11064-007-9506-7 View abstract

Grattan, D.R., Steyn, F.J., Kokay, I.C., Anderson, G.M., Bunn, S.J. Pregnancy-induced adaptation in the neuroendocrine control of prolactin secretion. (2008). J Neuroendocrinol, 20 (4), pp. 497-507. DOI: 10.1111/j.1365-2826.2008.01661.x View abstract

Larsen, C.M., Kokay, I.C., Grattan, D.R. Male pheromones initiate prolactin-induced neurogenesis and advance maternal behavior in female mice. (2008). Horm Behav, 53 (4), pp. 509-517. DOI: 10.1016/j.yhbeh.2007.11.020 View abstract

Herbison, A.E. Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: The case for the rostral periventricular area of the third ventricle (RP3V). (2008). Brain Res Re, 57 (2), pp. 277-287. DOI: 10.1016/j.brainresrev.2007.05.006 View abstract

Augustine, R.A., Grattan, D.R. Induction of central leptin resistance in hyperphagic pseudopregnant rats by chronic prolactin infusion. (2008). Endocrinology, 149 (3), pp. 1049-1055. DOI: 10.1210/en.2007-1018 View abstract

Han, S.-K., Herbison, A.E. Norepinephrine suppresses gonadotropin-releasing hormone neuron excitability in the adult mouse. (2008). Endocrinology, 149 (3), pp. 1129-1135. DOI: 10.1210/en.2007-1241 View abstract

Herbison, A.E., Porteous, R., Pape, J.-R., Mora, J.M., Hurst, P.R. Gonadotropin-releasing hormone neuron requirements for puberty, ovulation, and fertility. (2008). Endocrinology, 149 (2), pp. 597-604. DOI: 10.1210/en.2007-1139 View abstract

Ladyman SR. Leptin resistance during pregnancy in the rat. (2008). J Neuroendocrinol, 20, pp. 269-77. View abstract

Augustine, R.A., Ladyman, S.R., Grattan, D.R. From feeding one to feeding many: Hormone-induced changes in bodyweight homeostasis during pregnancy. (2008). J Physiol, 586 (2), pp. 387-397. DOI: 10.1113/jphysiol.2007.146316 View abstract

Washington, J.W., Henderson, W.M., Ellington, J.J., Jenkins, T.M., Evans, J.J. Analysis of perfluorinated carboxylic acids in soils II: Optimization of chromatography and extraction. (2008) J Chromatogr A, 1181 (1-2), pp. 21-32. DOI: 10.1016/j.chroma.2007.12.042 View abstract

Woodside B, Augustine RA, Ladyman SR, Naef L, and Grattan DR. Role of prolactin in the metabolic adaptations to pregnancy and lactation. In: Bridges RS Ed, The Parental Brain, Chap 16. pp 249-268. Academic Press, Burlington, MA (2008)

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Jasoni, C.L., Todman, M.G., Strumia, M.M., Herbison, A.E. Cell type-specific expression of a genetically encoded calcium indicator reveals intrinsic calcium oscillations in adult gonadotropin-releasing hormone neurons. (2007) J Neurosci, 27 (4), pp. 860-867. DOI: 10.1523/JNEUROSCI.3579-06.2007 View abstract

CNE Best Paper of the Year 2007

Campbell, R.E., Herbison, A.E. Definition of brainstem afferents to gonadotropin-releasing hormone neurons in the mouse using conditional viral tract tracing. (2007) Endocrinology, 148 (12), pp. 5884-5890. DOI: 10.1210/en.2007-0854 View abstract

RE Campbell. (2007). Young Investigator Perspectives: Defining the gonadotropin-releasing hormone (GnRH) neuronal network: Transgenic approaches to understanding neurocircuitry. J Neuroendocrinol, 19(7): 561-573. View abstract

Papp, A.M., Nyilas, R., Szepesi, Z., Lörincz, M.L., Takács, E., Ábrahám, I., Szilágyi, N., Tóth, J., Medveczky, P., Szilágyi, L., Juhász, G. and Juhász, G. Visible light induces matrix metalloproteinase-9 expression in rat eye, 2007, J Neurochem, 103:2224-33. DOI: 10.1111/j.1471-4159.2007.04917.x View abstract

Herbison, A.E. Genetics of puberty. (2007) Horm Res, 68 Suppl 5, pp. 75-79. DOI: 10.1159/000110583 View abstract

Brown, C.H., Scott, V., Ludwig, M., Leng, G., Bourque, C.W. Somatodendritic dynorphin release: Orchestrating activity patterns of vasopressin neurons. (2007) Biochem Soc Trans, 35 (5), pp. 1236-1242. DOI: 10.1042/BST0351236 View abstract

Steyn, F.J., Anderson, G.M., Grattan, D.R. Expression of ovarian steroid hormone receptors in tuberoinfundibular dopaminergic neurones during pregnancy and lactation. (2007) J Neuroendocrinol, 19 (10), pp. 788-793. DOI: 10.1111/j.1365-2826.2007.01590.x View abstract

Alkaisi MM, Muys JJ, Evans JJ (2007) Bioimprint of single cells on a biochip. Progress in Biomedical Optics and Imaging 8, 67990V1-10.

Grattan, D.R., Jasoni, C.L., Liu, X., Anderson, G.M., Herbison, A.E. Prolactin regulation of gonadotropin-releasing hormone neurons to suppress luteinizing hormone secretion in mice. (2007) Endocrinology, 148 (9), pp. 4344-4351. DOI: 10.1210/en.2007-0403 View abstract

Josephs, T., Waugh, H., Kokay, I., Grattan, D., Thompson, M. Fasting-induced adipose factor identified as a key adipokine that is up-regulated in white adipose tissue during pregnancy and lactation in the rat. (2007) J Neuroendocrinol, 194 (2), pp. 305-312. DOI: 10.1677/JOE-07-0158 View abstract

Brown, C.H., Grattan, D.R. Does maternal oxytocin protect the fetal brain? (2007) Trends Endocrinol Metab, 18 (6), pp. 225-226. DOI: 10.1016/j.tem.2007.04.003 View abstract

Savigny, P., Evans, J., McGrath, K.M. Cell membrane structures during exocytosis. (2007) Endocrinology, 148 (8), pp. 3863-3874. DOI: 10.1210/en.2006-1644 View abstract

Grattan, D.R., Ladyman, S.R., Augustine, R.A. Hormonal induction of leptin resistance during pregnancy. (2007) Physiol Behav, 91 (4), pp. 366-374. DOI: 10.1016/j.physbeh.2007.04.005 View abstract

Washington, J.W., Ellington, J.J., Jenkins, T.M., Evans, J.J. Analysis of perfluorinated carboxylic acids in soils: Detection and quantitation issues at low concentrations. (2007) J Chromatogr A, 1154 (1-2), pp. 111-120. DOI: 10.1016/j.chroma.2007.03.107 View abstract

Möderscheim, T.A.E., Gorba, T., Pathipati, P., Kokay, I.C., Grattan, D.R., Williams, C.E., Scheepens, A. Prolactin is involved in glial responses following a focal injury to the juvenile rat brain. (2007) Neuroscience, 145 (3), pp. 963-973. DOI: 10.1016/j.neuroscience.2006.12.053 View abstract

Steyn, F.J., Anderson, G.M., Grattan, D.R. Differential effects of centrally-administered oestrogen antagonist ICI-182,780 on oestrogen-sensitive functions in the hypothalamus. (2007) J Neuroendocrinol, 19 (1), pp. 26-33. DOI: 10.1111/j.1365-2826.2006.01499.x View abstract

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Clarkson, J., Herbison, A.E. Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons. (2006) Endocrinology, 147 (12), pp. 5817-5825. DOI: 10.1210/en.2006-0787 View abstract

Muys, J.J., Alkaisi, M.M., Evans, J.J. Bioimprint. (2006) Proceedings of the 2006 International Conference on Nanoscience and Nanotechnology, ICONN, art. no. 4143390, pp. 294-297. DOI: 10.1109/ICONN.2006.340610

Wintermantel, T.M., Elzer, J., Herbison, A.E., Fritzemeier, K.H., Schütz, G. Genetic dissection of estrogen receptor signaling in vivo. (2006) Ernst Schering Foundation symposium proceedings, 1, pp. 25-44. View abstract

Wintermantel, T.M., Campbell, R.E., Porteous, R., Bock, D., Gröne, H.-J., Todman, M.G., Korach, K.S., Greiner, E., Pérez, C.A., Schütz, G., Herbison, A.E. Definition of Estrogen Receptor Pathway Critical for Estrogen Positive Feedback to Gonadotropin-Releasing Hormone Neurons and Fertility. (2006) Neuron, 52 (2), pp. 271-280. DOI: 10.1016/j.neuron.2006.07.023 View abstract

Pearson, L.J., Rait, C., Nicholls, M.G., Yandle, T.G., Evans, J.J. Regulation of adrenomedullin release from human endothelial cells by sex steroids and angiotensin-II. (2006) J Endocrinol, 191 (1), pp. 171-177. DOI: 10.1677/joe.1.06815 View abstract

Anderson, G.M., Beijer, P., Bang, A.S., Fenwick, M.A., Bunn, S.J., Grattan, D.R. Suppression of prolactin-induced signal transducer and activator of transcription 5b signaling and induction of suppressors of cytokine signaling messenger ribonucleic acid in the hypothalamic arcuate nucleus of the rat during late pregnancy and lactation. (2006) Endocrinology, 147 (10), pp. 4996-5005. DOI: 10.1210/en.2005-0755 View abstract

Ábrahám, IM, Meerlo, P., Luiten, P.G.M. Concentration dependent actions of glucocorticoids on neuronal viability and survival. (2006) Dose-Response, Invited Review, 4, pp. 38-54. DOI: 10.2203/dose-response.004.01.004.Ábrahám View abstract

Anderson, G.M., Grattan, D.R., Van Den Ancker, W., Bridges, R.S. Reproductive experience increases prolactin responsiveness in the medial preoptic area and arcuate nucleus of female rats. (2006) Endocrinology, 147 (10), pp. 4688-4694. DOI: 10.1210/en.2006-0600 View abstract

Szegő, É.M., Barabás, K., Balog, J., Szilágyi, N., Korach, K.S., Juhász, G., Ábrahám, I.M. Estrogen induces estrogen receptor α-dependent cAMP response element-binding protein phosphorylation via mitogen activated protein kinase pathway in basal forebrain cholinergic neurons in vivo. (2006) J Neurosci, 26 (15), pp. 4104-4110. DOI: 10.1523/JNEUROSCI.0222-06.2006 View abstract

Muys, J.J., Alkaisi, M.M., Evans, J.J. Cellular replication and atomic force microscope imaging using a UV-Bioimprint technique. (2006) Nanomedicine: Nanotechnology, Biology, and Medicine, 2 (3), pp. 169-176. DOI: 10.1016/j.nano.2006.07.003 View abstract

Barabás K, Szegő M.É Kaszás A. Nagy M G, Juhász G, Ábrahám. IM. Sex differences in estrogen-induced p44/42 MAPK phosphorylation in the mouse brain in vivo. (2006) J Neuroendocrinol, 18, pp. 621-8. DOI: 10.1111/j.1365-2826.2006.01447 View abstract

Clarkson, J., Herbison, A.E. Development of GABA and glutamate signaling at the GnRH neuron in relation to puberty. (2006) Mol Cell Endocrinol, 254-255, pp. 32-38. DOI: 10.1016/j.mce.2006.04.036 View abstract

Cottrell, E.C., Campbell, R.E., Han, S.-K., Herbison, A.E. Postnatal remodeling of dendritic structure and spine density in gonadotropin-releasing hormone neurons. (2006) Endocrinology, 147 (8), pp. 3652-3661. DOI: 10.1210/en.2006-0296 View abstract

Bull, P.M., Brown, C.H., Russell, J.A., Ludwig, M. Activity-dependent feedback modulation of spike patterning of supraoptic nucleus neurons by endogenous adenosine. (2006) Am J Physiol Regul Integr Comp Physiol, 291 (1), pp. R83-R90. DOI: 10.1152/ajpregu.00744.2005 View abstract

Kovács Z, Kékesi KA, Szilágyi N, Ábrahám I, Székács D, Király N, Papp E, Császár I, Szego E, Barabás K, Péterfy H, Erdei A, Bártfai T, Juhász G. Facilitation of spike-wave discharge activity by lipopolysaccharides in Wistar Albino Glaxo/Rijswijk rats. (2006). Neuroscience 140 (2), pp. 731-42. DOI: 10.1016/j.neuroscience.2006.02.023 View abstract

Brown, C.H., Leng, G., Ludwig, M., Bourque, C.W. Endogenous activation of supraoptic nucleus κ-opioid receptors terminates spontaneous phasic bursts in rat magnocellular neurosecretory cells. (2006). J Neurophysiol, 95 (5), pp. 3235-3244. DOI: 10.1152/jn.00062.2006 View abstract

Brown, C.H., Bourque, C.W. Mechanisms of rhythmogenesis: Insights from hypothalamic vasopressin neurons. (2006). Trends Neurosci, 29 (2), pp. 108-115. DOI: 10.1016/j.tins.2005.11.005 View abstract

Kokay, I.C., Bull, P.M., Davis, R.L., Ludwig, M., Grattan, D.R. Expression of the long form of the prolactin receptor in magnocellular oxytocin neurons is associated with specific prolactin regulation of oxytocin neurons. (2006) Am J Physiol Regul Integr Comp Physiol, 290 (5), pp. R1216-R1225. DOI: 10.1152/ajpregu.00730.2005 View abstract

O'Sullivan, K.M., Bunn, S.J. Phospholipase C isozymes are differentially distributed in the rat adrenal medulla. (2006) Neurosci Lett, 396 (3), pp. 212-216. DOI: 10.1016/j.neulet.2005.11.033 View abstract

Andrews, Z.B., Zhao, H., Frugier, T., Meguro, R., Grattan, D.R., Koishi, K., McLennan, I.S. Transforming growth factor beta2 haploinsufficient mice develop age-related nigrostriatal dopamine deficits. (2006) Neurobiol Dis, 21 (3), pp. 568-575. DOI: 10.1016/j.nbd.2005.09.001 View abstract

Sundberg, S.E., Ellington, J.J., Evans, J.J. A simple and fast extraction method for organochlorine pesticides and polychlorinated biphenyls in small volumes of avian serum. (2006). J Chromatogr B, 831 (1-2), pp. 99-104. DOI: 10.1016/j.jchromb.2005.11.037 View abstract

Muys, J.J., Alkaisi, M.M., Melville, D.O.S., Nagase, J., Sykes, P., Parguez, G.M., Evans, J.J. Cellular transfer and AFM imaging of cancer cells using Bioimprint. (2006). J Nanobiotechnology, 4, art. no. 1, p. 10. DOI: 10.1186/1477-3155-4-1 View abstract

O'Sullivan, K.M. and Bunn, S.J. Phospholipase C isozymes are differentially distributed in the rat adrenal medulla. (2006). Neurosci Lett, 396, pp. 212-216. DOI: 10.1016/j.neulet.2005.11.033 View abstract

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Jasoni, C.L., Todman, M.G., Han, S.-K., Herbison, A.E. Expression of mRNAs encoding receptors that mediate stress signals in gonadotropin-releasing hormone neurons of the mouse. (2005) Neuroendocrinology, 82, (5-6), pp. 320-328. DOI: 10.1159/000093155 View abstract

Han, S.-K., Gottsch, M.L., Lee, K.J., Popa, S.M., Smith, J.T., Jakawich, S.K., Clifton, D.K., Steiner, R.A., Herbison, A.E. Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty. (2005) J Neurosci, 25 (49), pp. 11349-11356. DOI: 10.1523/JNEUROSCI.3328-05.2005 View abstract

Ma, F.Y., Anderson, G.M., Gunn, T.D., Goffin, V., Grattan, D.R., Bunn, S.J. Prolactin specifically activates signal transducer and activator of transcription 5b in neuroendocrine dopaminergic neurons. (2005) Endocrinology, 146 (12), pp. 5112-5119. DOI: 10.1210/en.2005-0770 View abstract

Kokay, I.C., Grattan, D.R. Expression of mRNA for prolactin receptor (long form) in dopamine and pro-opiomelanocortin neurones in the arcuate nucleus of non-pregnant and lactating rats. (2005) J Neuroendocrinol, 17 (12), pp. 827-835. DOI: 10.1111/j.1365-2826.2005.01374.x View abstract

Ladyman, S.R., Grattan, D.R. Suppression of leptin receptor mRNA and leptin responsiveness in the ventromedial nucleus of the hypothalamus during pregnancy in the rat. (2005) Endocrinology, 146 (9), pp. 3868-3874. DOI: 10.1210/en.2005-0194 View abstract

Muys, J., Alkaisi, M.M., Evans, J.J., Nagase, J. Biochip: Cellular analysis by atomic force microscopy using dielectrophoretic manipulation. (2005) Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers, 44 (7 B), pp. 5717-5723. DOI: 10.1143/JJAP.44.5717

Todman, M.G., Han, S.-K., Herbison, A.E. Profiling neurotransmitter receptor expression in mouse gonadotropin-releasing hormone neurons using green fluorescent protein-promoter transgenics and microarrays. (2005) Neuroscience, 132 (3), pp. 703-712. DOI: 10.1016/j.neuroscience.2005.01.035 View abstract

Gamble, J.A., Karunadasa, D.K., Pape, J.-R., Skynner, M.J., Todman, M.G., Bicknell, R.J., Allen, J.P., Herbison, A.E. Disruption of ephrin signaling associates with disordered axophilic migration of the gonadotropin-releasing hormone neurons. (2005) J Neurosci, 25 (12), pp. 3142-3150. DOI: 10.1523/JNEUROSCI.4759-04.2005 View abstract

Ábrahám, I.M., Herbison, A.E. Major sex differences in non-genomic estrogen actions on intracellular signaling in mouse brain in vivo. (2005) Neuroscience, 131 (4), pp. 945-951. DOI: 10.1016/j.neuroscience.2004.10.046 View abstract

Campbell, R.E., Han, S.-K., Herbison, A.E. Biocytin filling of adult gonadotropin-releasing hormone neurons in situ reveals extensive, spiny, dendritic processes. (2005) Endocrinology, 146 (3), pp. 1163-1169. DOI: 10.1210/en.2004-1369 View abstract

Ma, E., Lau, J., Grattan, D.R., Lovejoy, D.A., Wynne-Edwards, K.E. Male and female prolactin receptor mRNA expression in the brain of a biparental and a uniparental hamster, Phodopus, before and after the birth of a litter. (2005) J Neuroendocrinol, 17 (2), pp. 81-90. DOI: 10.1111/j.1365-2826.2005.01278.x View abstract

Ma, F.Y., Grattan, D.R., Goffin, V., Bunn, S.J. Prolactin-regulated tyrosine hydroxylase activity and messenger ribonucleic acid expression in mediobasal hypothalamic cultures: The differential role of specific protein kinases. (2005) Endocrinology, 146 (1), pp. 93-102. DOI: 10.1210/en.2004-0800 View abstract

Brown, C.H., Stern, J.E., Jackson, K.L.M., Bull, P.M., Leng, G., Russell, J.A. Morphine withdrawal increases intrinsic excitability of oxytocin neurons in morphine-dependent rats. (2005) Eur J Neurosci, 21 (2), pp. 501-512. DOI: 10.1111/j.1460-9568.2005.03885.x View abstract

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Muys, J., Alkaisi, M.M., Evans, J.J., Nagase, J. Biochip: Cellular analysis by Atomic Force Microscopy using dielectrophoretic separation and manipulation. (2004) Digest of Papers - Microprocesses and Nanotechnology 2004, pp. 222-223.

Roberts-Thomson, E.L., Herd, L.M., Saunders, H.I., Dunkley, P.R., Bunn, S.J. The tryrosine phosphorylation and cytoskeletal translocation of phospholipase Cγ1 in bovine adrenal medullary chromaffin cells. (2004) Neurochem Res, 29 (10), pp. 1847-1855. DOI: 10.1023/B:NERE.0000042211.76499.c6 View abstract

Abbas, M.M., Evans, J.J., Sykes, P.H., Benny, P.S. Modulation of vascular endothelial growth factor and thymidine phosphorylase in normal human endometrial stromal cells. (2004) Fertil Steril, 82 (SUPPL. 3), pp. 1048-1053. DOI: 10.1016/j.fertnstert.2004.02.135 View abstract

Andrews, Z.B., Grattan, D.R. The roles of dopamine and the neurointermediate lobe of the pituitary in the regulation of prolactin secretion during late pregnancy in rats. (2004) J Neuroendocrinol, 16 (10), pp. 859-865. DOI: 10.1111/j.1365-2826.2004.01241.x View abstract

Brown, C.H. Rhythmogenesis in vasopressin cells. (2004) J Neuroendocrinol, 16 (9), pp. 727-739. DOI: 10.1111/j.1365-2826.2004.01227.x View abstract

Ladyman, S.R., Grattan, D.R. Region-specific reduction in leptin-induced phosphorylation of signal transducer and activator of transcription-3 (STAT3) in the rat hypothalamus is associated with leptin resistance during pregnancy. (2004) Endocrinology, 145 (8), pp. 3704-3711. DOI: 10.1210/en.2004-0338 View abstract

Johnstone, L.E., Leng, G., Brown, C.H. Effects of neurotensin on the organization of activity in supraoptic nucleus cells in virgin and lactating rats. (2004) J Neuroendocrinol, 16 (7), pp. 605-611. DOI: 10.1111/j.1365-2826.2004.01208.x View abstract

Sabatier, N., Brown, C.H., Ludwig, M., Leng, G. Phasic spike patterning in rat supraoptic neurones in vivo and in vitro. (2004) J Physiol, 558 (1), pp. 161-180. DOI: 10.1113/jphysiol.2004.063982 View abstract

Ábrahám, I.M., Todman, M.G., Korach, K.S., Herbison, A.E. Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in mouse brain. (2004) Endocrinology, 145 (7), pp. 3055-3061. DOI: 10.1210/en.2003-1676 View abstract

Ma, F.Y., Grattan, D.R., Bobrovskaya, L., Dunkley, P.R., Bunn, S.J. Angiotensin II regulates tyrosine hydroxylase activity and mRNA expression in rat mediobasal hypothalamic cultures: The role of specific protein kinases. (2004) J Neurochem, 90 (2), pp. 431-441. DOI: 10.1111/j.1471-4159.2004.02492.x View abstract

Brown, C.H., Bourque, C.W. Autocrine feedback inhibition of plateau potentials terminates phasic bursts in magnocellular neurosecretory cells of the rat supraoptic nucleus. (2004) J Physiol, 557 (3), pp. 949-960. DOI: 10.1113/jphysiol.2004.063818 View abstract

Brown, C.H., Russell, J.A. Cellular mechanisms underlying neuronal excitability during morphine withdrawal in physical dependence: Lessons from the magnocellular oxytocin system. (2004) Stress, 7 (2), pp. 97-107. DOI: 10.1080/10253890410001727776 View abstract

Goodman, R.L., Coolen, L.M., Anderson, G.M., Hardy, S.L., Valent, M., Connors, J.M., Fitzgerald, M.E., Lehman, M.N. Evidence that dynorphin plays a major role in mediating progesterone negative feedback on gonadotropin-releasing hormone neurons in sheep. (2004) Endocrinology, 145 (6), pp. 2959-2967. DOI: 10.1210/en.2003-1305 View abstract

Brown, C.H., Bull, P.M., Bourque, C.W. Phasic bursts in rat magnocellular neurosecretory cells are not intrinsically regenerative in vivo. (2004) Eur J Neurosci, 19 (11), pp. 2977-2983. DOI: 10.1111/j.0953-816X.2004.03408.x View abstract

Namciu, S.J., Friedman, R.D., Marsden, M.D., Sarausad, L.M., Jasoni, C.L., Fournier, R.E.K. Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1. (2004) Mamm Genome, 15 (3), pp. 162-178. DOI: 10.1007/s00335-003-2311-y View abstract

Brown, C.H., Ludwig, M., Leng, G. Temporal dissociation of the feedback effects of dendritically co-released peptides on rhythmogenesis in vasopressin cells. (2004) Neuroscience, 124 (1), pp. 105-111. DOI: 10.1016/j.neuroscience.2003.11.038 View abstract

Han, S.-K., Todman, M.G., Herbison, A.E. Endogenous GABA Release Inhibits the Firing of Adult Gonadotropin- Releasing Hormone Neurons. (2004) Endocrinology, 145 (2), pp. 495-499. DOI: 10.1210/en.2003-1333 View abstract

Engelmann, M., Bull, P.M., Brown, C.H., Landgraf, R., Horn, T.F.W., Singewald, N., Ludwig, M., Wotjak, C.T. GABA selectively controls the secretory activity of oxytocin neurons in the rat supraoptic nucleus. (2004) Eur J Neurosci, 19 (3), pp. 601-608. DOI: 10.1111/j.1460-9568.2004.03151.x View abstract

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Dorling, A.A., Todman, M.G., Korach, K.S., Herbison, A.E. Critical role for estrogen receptor alpha in negative feedback regulation of gonadotropin-releasing hormone mRNA expression in the female mouse. (2003) Neuroendocrinology, 78 (4), pp. 204-209. DOI: 10.1159/000073703 View abstract

Abbas, M.M., Evans, J.J., Sin, I.L., Gooneratne, A., Hill, A., Benny, P.S. Vascular endothelial growth factor and leptin: Regulation in human cumulus cells and in follicles. (2003)Acta Obstet Gynecol Scand, 82 (11), pp. 997-1003. DOI: 10.1034/j.1600-0412.2003.00304.x View abstract

Bull, P.M., Ludwig, M., Blackburn-Munro, G.J., Delgado-Cohen, H., Brown, C.H., Russell, J.A. The role of nitric oxide in morphine dependence and withdrawal excitation of rat oxytocin neurons. (2003) Eur J Neurosci, 18 (9), pp. 2545-2551. DOI: 10.1046/j.1460-9568.2003.03005.x View abstract

Tompkins, M.M., Gai, W.P., Douglas, S., Bunn, S.J. α-synuclein expression localizes to the Golgi apparatus in bovine adrenal medullary chromaffin cells. (2003) Brain Research, 984 (1-2), pp. 233-236. DOI: 10.1016/S0006-8993(03)03040-3 View abstract

Anderson, G.M., Lapwood, K.R., Knight, P.G., Parkinson, T.J. The reproductive response of rams to thyroidectomy: Mediation by impaired inhibin feedback rather than a change in LH pulsatility. (2003) Reproduction, 126 (3), pp. 353-364. View abstract

Thanky, N.R., Slater, R., Herbison, A.E. Sex differences in estrogen-dependent transcription of gonadotropin-releasing hormone (GnRH) gene revealed in GnRH transgenic mice. (2003) Endocrinology, 144 (8), pp. 3351-3358. DOI: 10.1210/en.2001-211342 View abstract

Augustine, R.A., Kokay, I.C., Andrews, Z.B., Ladyman, S.R., Grattan, D.R. Quantitation of prolactin receptor mRNA in the maternal rat brain during pregnancy and lactation. (2003) J Mol Endocrinol, 31 (1), pp. 221-232. DOI: 10.1677/jme.0.0310221 View abstract

Ábrahám, I.M., Han, S.-K., Todman, M.G., Korach, K.S., Herbison, A.E. Estrogen receptor β mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo. (2003) J Neurosci, 23 (13), pp. 5771-5777. View abstract

Evans, J.J., Reid, R.A., Wakeman, S.A., Croft, L.B., Benny, P.S. Evidence that oxytocin is a physiological component of LH regulation in non-pregnant women. (2003)Hum Reprod, 18 (7), pp. 1428-1431. DOI: 10.1093/humrep/deg291 View abstract

Anderson, G.M., Hardy, S.L., Valent, M., Billings, H.J., Connors, J.M., Goodman, R.L. Evidence that thyroid hormones act in the ventromedial preoptic area and the premammillary region of the brain to allow the termination of the breeding season in the ewe. (2003) Endocrinology, 144 (7), pp. 2892-2901. DOI: 10.1210/en.2003-0322 View abstract

Bridges, R.S., Grattan, D.R. Prolactin-induced neurogenesis in the maternal brain. 2003) Trends in Endocrinology and Metabolism, 14 (5), pp. 199-201. DOI: 10.1016/S1043-2760(03)00082-1 View abstract

Anderson, S.T., Kokay, I.C., Lang, T., Grattan, D.R., Curlewis, J.D. Quantification of prolactin-releasing peptide (PrRP) mRNA expression in specific brain regions of the rat during the oestrous cycle and in lactation. (2003) Brain Research, 973 (1), pp. 64-73. DOI: 10.1016/S0006-8993(03)02543-5 View abstract

O'Connell, G.C., Douglas, S.A., Bunn, S.J. The involvement of specific phospholipase C isozymes in catecholamine release from digitonin permeabilized bovine adrenal medullary chromaffin cells. (2003) Neurosci Lett, 342 (1-2), pp. 1-4. DOI: 10.1016/S0304-3940(03)00224-6 View abstract

Evans, J.J., Youssef, A.H., Yandle, T.G., Lewis, L.K., Nicholls, M.G. Endothelin-1 directly modulates its own secretion: Studies utilising the cell immunoblot technique. (2003)Regul Pept, 113 (1-3), pp. 149-153. DOI: 10.1016/S0167-0115(03)00045-4 View abstract

Hardy, S.L., Anderson, G.M., Valent, M., Connors, J.M., Goodman, R.L. Evidence that estrogen receptor alpha, but not beta, mediates seasonal changes in the response of the ovine retrochiasmatic area to estradiol. (2003) Biol Reprod, 68 (3), pp. 846-852. DOI: 10.1095/biolreprod.102.010215 View abstract

Andrews, Z.B., Grattan, D.R. Opioid receptor subtypes involved in the regulation of prolactin secretion during pregnancy and lactation. (2003) J Neuroendocrinol, 15 (3), pp. 227-236. DOI: 10.1046/j.1365-2826.2003.00975.x View abstract

Todd, B.J., Ladyman, S.R., Grattan, D.R. Suppression of pulsatile luteinizing hormone secretion but not luteinizing hormone surge in leptin resistant obese Zucker rats. (2003) J Neuroendocrinol, 15 (1), pp. 61-68. DOI: 10.1046/j.1365-2826.2003.00871.x View abstract

Centre for Neuroendocrinology Centre for Neuroendocrinology University of Otago